One of the characteristics of ageing is the occurrence of chronic low-grade inflammation. This slight but chronic increase in inflammatory substances in the bloodstream is caused by ageing processes in the immune system, an increase in fat mass and a sedentary lifestyle. Chronic low-grade inflammation accelerates the occurrence of chronic diseases such as cardiovascular diseases, diabetes, osteoarthritis, etc.
Chronic low-grade inflammation also has an influence on muscle strength and mass and increases the vulnerability of older people, thus reducing their independence. Preventing or curing chronic low-grade inflammation therefore contributes to healthy ageing.
The European PROVIDE study investigates the effects of dietary supplements containing vitamin D and proteins in elderly people with reduced mobility. Older people often lack vitamin D and proteins. Vitamin D can be found in fish, but it is also produced after exposure to UV sun exposure. In the winter, when there is little natural sunlight, a vitamin D supplement is often recommended. Proteins can be found in milk products, eggs, chicken white or legumes. The PROVIDE study has already shown, among other things, that the administration of vitamin D and protein supplements has a positive effect on muscle mass in older people.